TY - JOUR T1 - Computerized adaptive testing in back pain: Validation of the CAT-5D-QOL JF - Spine Y1 - 2008 A1 - Kopec, J. A. A1 - Badii, M. A1 - McKenna, M. A1 - Lima, V. D. A1 - Sayre, E. C. A1 - Dvorak, M. KW - *Disability Evaluation KW - *Health Status Indicators KW - *Quality of Life KW - Adult KW - Aged KW - Algorithms KW - Back Pain/*diagnosis/psychology KW - British Columbia KW - Diagnosis, Computer-Assisted/*standards KW - Feasibility Studies KW - Female KW - Humans KW - Internet KW - Male KW - Middle Aged KW - Predictive Value of Tests KW - Questionnaires/*standards KW - Reproducibility of Results AB - STUDY DESIGN: We have conducted an outcome instrument validation study. OBJECTIVE: Our objective was to develop a computerized adaptive test (CAT) to measure 5 domains of health-related quality of life (HRQL) and assess its feasibility, reliability, validity, and efficiency. SUMMARY OF BACKGROUND DATA: Kopec and colleagues have recently developed item response theory based item banks for 5 domains of HRQL relevant to back pain and suitable for CAT applications. The domains are Daily Activities (DAILY), Walking (WALK), Handling Objects (HAND), Pain or Discomfort (PAIN), and Feelings (FEEL). METHODS: An adaptive algorithm was implemented in a web-based questionnaire administration system. The questionnaire included CAT-5D-QOL (5 scales), Modified Oswestry Disability Index (MODI), Roland-Morris Disability Questionnaire (RMDQ), SF-36 Health Survey, and standard clinical and demographic information. Participants were outpatients treated for mechanical back pain at a referral center in Vancouver, Canada. RESULTS: A total of 215 patients completed the questionnaire and 84 completed a retest. On average, patients answered 5.2 items per CAT-5D-QOL scale. Reliability ranged from 0.83 (FEEL) to 0.92 (PAIN) and was 0.92 for the MODI, RMDQ, and Physical Component Summary (PCS-36). The ceiling effect was 0.5% for PAIN compared with 2% for MODI and 5% for RMQ. The CAT-5D-QOL scales correlated as anticipated with other measures of HRQL and discriminated well according to the level of satisfaction with current symptoms, duration of the last episode, sciatica, and disability compensation. The average relative discrimination index was 0.87 for PAIN, 0.67 for DAILY and 0.62 for WALK, compared with 0.89 for MODI, 0.80 for RMDQ, and 0.59 for PCS-36. CONCLUSION: The CAT-5D-QOL is feasible, reliable, valid, and efficient in patients with back pain. This methodology can be recommended for use in back pain research and should improve outcome assessment, facilitate comparisons across studies, and reduce patient burden. VL - 33 SN - 1528-1159 (Electronic)0362-2436 (Linking) N1 - Kopec, Jacek ABadii, MaziarMcKenna, MarioLima, Viviane DSayre, Eric CDvorak, MarcelResearch Support, Non-U.S. Gov'tValidation StudiesUnited StatesSpineSpine (Phila Pa 1976). 2008 May 20;33(12):1384-90. ER - TY - JOUR T1 - Computerized adaptive testing of diabetes impact: a feasibility study of Hispanics and non-Hispanics in an active clinic population JF - Quality of Life Research Y1 - 2006 A1 - Schwartz, C. A1 - Welch, G. A1 - Santiago-Kelley, P. A1 - Bode, R. A1 - Sun, X. KW - *Computers KW - *Hispanic Americans KW - *Quality of Life KW - Adult KW - Aged KW - Data Collection/*methods KW - Diabetes Mellitus/*psychology KW - Feasibility Studies KW - Female KW - Humans KW - Language KW - Male KW - Middle Aged AB - BACKGROUND: Diabetes is a leading cause of death and disability in the US and is twice as common among Hispanic Americans as non-Hispanics. The societal costs of diabetes provide an impetus for developing tools that can improve patient care and delay or prevent diabetes complications. METHODS: We implemented a feasibility study of a Computerized Adaptive Test (CAT) to measure diabetes impact using a sample of 103 English- and 97 Spanish-speaking patients (mean age = 56.5, 66.5% female) in a community medical center with a high proportion of minority patients (28% African-American). The 37 items of the Diabetes Impact Survey were translated using forward-backward translation and cognitive debriefing. Participants were randomized to receive either the full-length tool or the Diabetes-CAT first, in the patient's native language. RESULTS: The number of items and the amount of time to complete the survey for the CAT was reduced to one-sixth the amount for the full-length tool in both languages, across disease severity. Confirmatory Factor Analysis confirmed that the Diabetes Impact Survey is unidimensional. The Diabetes-CAT demonstrated acceptable internal consistency reliability, construct validity, and discriminant validity in the overall sample, although subgroup analyses suggested that the English sample data evidenced higher levels of reliability and validity than the Spanish sample and issues with discriminant validity in the Spanish sample. Differential Item Function analysis revealed differences in responses tendencies by language group in 3 of the 37 items. Participant interviews suggested that the Spanish-speaking patients generally preferred the paper survey to the computer-assisted tool, and were twice as likely to experience difficulties understanding the items. CONCLUSIONS: While the Diabetes-CAT demonstrated clear advantages in reducing respondent burden as compared to the full-length tool, simplifying the item bank will be necessary for enhancing the feasibility of the Diabetes-CAT for use with low literacy patients. VL - 15 SN - 0962-9343 (Print) N1 - Schwartz, CarolynWelch, GarrySantiago-Kelley, PaulaBode, RitaSun, Xiaowu1 r43 dk066874-01/dk/niddkResearch Support, N.I.H., ExtramuralNetherlandsQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitationQual Life Res. 2006 Nov;15(9):1503-18. Epub 2006 Sep 26. ER - TY - JOUR T1 - The feasibility of applying item response theory to measures of migraine impact: a re-analysis of three clinical studies JF - Quality of Life Research Y1 - 2003 A1 - Bjorner, J. B. A1 - Kosinski, M. A1 - Ware, J. E., Jr. KW - *Sickness Impact Profile KW - Adolescent KW - Adult KW - Aged KW - Comparative Study KW - Cost of Illness KW - Factor Analysis, Statistical KW - Feasibility Studies KW - Female KW - Human KW - Male KW - Middle Aged KW - Migraine/*psychology KW - Models, Psychological KW - Psychometrics/instrumentation/*methods KW - Quality of Life/*psychology KW - Questionnaires KW - Support, Non-U.S. Gov't AB - BACKGROUND: Item response theory (IRT) is a powerful framework for analyzing multiitem scales and is central to the implementation of computerized adaptive testing. OBJECTIVES: To explain the use of IRT to examine measurement properties and to apply IRT to a questionnaire for measuring migraine impact--the Migraine Specific Questionnaire (MSQ). METHODS: Data from three clinical studies that employed the MSQ-version 1 were analyzed by confirmatory factor analysis for categorical data and by IRT modeling. RESULTS: Confirmatory factor analyses showed very high correlations between the factors hypothesized by the original test constructions. Further, high item loadings on one common factor suggest that migraine impact may be adequately assessed by only one score. IRT analyses of the MSQ were feasible and provided several suggestions as to how to improve the items and in particular the response choices. Out of 15 items, 13 showed adequate fit to the IRT model. In general, IRT scores were strongly associated with the scores proposed by the original test developers and with the total item sum score. Analysis of response consistency showed that more than 90% of the patients answered consistently according to a unidimensional IRT model. For the remaining patients, scores on the dimension of emotional function were less strongly related to the overall IRT scores that mainly reflected role limitations. Such response patterns can be detected easily using response consistency indices. Analysis of test precision across score levels revealed that the MSQ was most precise at one standard deviation worse than the mean impact level for migraine patients that are not in treatment. Thus, gains in test precision can be achieved by developing items aimed at less severe levels of migraine impact. CONCLUSIONS: IRT proved useful for analyzing the MSQ. The approach warrants further testing in a more comprehensive item pool for headache impact that would enable computerized adaptive testing. VL - 12 N1 - 0962-9343Journal Article ER - TY - JOUR T1 - National Council Computerized Adaptive Testing Project Review--committee perspective JF - Issues Y1 - 1990 A1 - Haynes, B. KW - *Computers KW - *Licensure KW - Educational Measurement/*methods KW - Feasibility Studies KW - Societies, Nursing KW - United States VL - 11 N1 - 911613110885-0046Journal Article ER -