TY - JOUR T1 - Multidimensional computerized adaptive testing of the EORTC QLQ-C30: basic developments and evaluations JF - Quality of Life Research Y1 - 2006 A1 - Petersen, M. A. A1 - Groenvold, M. A1 - Aaronson, N. K. A1 - Fayers, P. A1 - Sprangers, M. A1 - Bjorner, J. B. KW - *Quality of Life KW - *Self Disclosure KW - Adult KW - Female KW - Health Status KW - Humans KW - Male KW - Middle Aged KW - Questionnaires/*standards KW - User-Computer Interface AB - OBJECTIVE: Self-report questionnaires are widely used to measure health-related quality of life (HRQOL). Ideally, such questionnaires should be adapted to the individual patient and at the same time scores should be directly comparable across patients. This may be achieved using computerized adaptive testing (CAT). Usually, CAT is carried out for a single domain at a time. However, many HRQOL domains are highly correlated. Multidimensional CAT may utilize these correlations to improve measurement efficiency. We investigated the possible advantages and difficulties of multidimensional CAT. STUDY DESIGN AND SETTING: We evaluated multidimensional CAT of three scales from the EORTC QLQ-C30: the physical functioning, emotional functioning, and fatigue scales. Analyses utilised a database with 2958 European cancer patients. RESULTS: It was possible to obtain scores for the three domains with five to seven items administered using multidimensional CAT that were very close to the scores obtained using all 12 items and with no or little loss of measurement precision. CONCLUSION: The findings suggest that multidimensional CAT may significantly improve measurement precision and efficiency and encourage further research into multidimensional CAT. Particularly, the estimation of the model underlying the multidimensional CAT and the conceptual aspects need further investigations. VL - 15 SN - 0962-9343 (Print) N1 - Petersen, Morten AaGroenvold, MogensAaronson, NeilFayers, PeterSprangers, MirjamBjorner, Jakob BEuropean Organisation for Research and Treatment of Cancer Quality of Life GroupResearch Support, Non-U.S. Gov'tNetherlandsQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitationQual Life Res. 2006 Apr;15(3):315-29. ER -