02128nas a2200181   4500008004100000020001300041245013400054210006900188300001200257490000700269520147700276100001601753700001501769700001401784700001601798700001401814856011801828       2006                        eng d  a0895435600aAn evaluation of a patient-reported outcomes found computerized adaptive testing was efficient in assessing osteoarthritis impact0 aevaluation of a patientreported outcomes found computerized adap  a715-7230 v593 aBACKGROUND AND OBJECTIVES: Evaluate a patient-reported outcomes questionnaire that uses computerized adaptive testing (CAT) to measure the impact of osteoarthritis (OA) on functioning and well-being. MATERIALS AND METHODS: OA patients completed 37 questions about the impact of OA on physical, social and role functioning, emotional well-being, and vitality. Questionnaire responses were calibrated and scored using item response theory, and two scores were estimated: a Total-OA score based on patients' responses to all 37 questions, and a simulated CAT-OA score where the computer selected and scored the five most informative questions for each patient. Agreement between Total-OA and CAT-OA scores was assessed using correlations. Discriminant validity of Total-OA and CAT-OA scores was assessed with analysis of variance. Criterion measures included OA pain and severity, patient global assessment, and missed work days. RESULTS: Simulated CAT-OA and Total-OA scores correlated highly (r = 0.96). Both Total-OA and simulated CAT-OA scores discriminated significantly between patients differing on the criterion measures. F-statistics across criterion measures ranged from 39.0 (P < .001) to 225.1 (P < .001) for the Total-OA score, and from 40.5 (P < .001) to 221.5 (P < .001) for the simulated CAT-OA score. CONCLUSIONS: CAT methods produce valid and precise estimates of the impact of OA on functioning and well-being with significant reduction in response burden.1 aKosinski, M1 aBjorner, J1 aWarejr, J1 aSullivan, E1 aStraus, W  uhttp://iacat.org/content/evaluation-patient-reported-outcomes-found-computerized-adaptive-testing-was-efficient-0