@article {237, title = {Factor analysis techniques for assessing sufficient unidimensionality of cancer related fatigue}, journal = {Quality of Life Research}, volume = {15}, number = {7}, year = {2006}, note = {0962-9343 (Print)Journal ArticleResearch Support, N.I.H., Extramural}, month = {Sep}, pages = {1179-90}, abstract = {BACKGROUND: Fatigue is the most common unrelieved symptom experienced by people with cancer. The purpose of this study was to examine whether cancer-related fatigue (CRF) can be summarized using a single score, that is, whether CRF is sufficiently unidimensional for measurement approaches that require or assume unidimensionality. We evaluated this question using factor analysis techniques including the theory-driven bi-factor model. METHODS: Five hundred and fifty five cancer patients from the Chicago metropolitan area completed a 72-item fatigue item bank, covering a range of fatigue-related concerns including intensity, frequency and interference with physical, mental, and social activities. Dimensionality was assessed using exploratory and confirmatory factor analysis (CFA) techniques. RESULTS: Exploratory factor analysis (EFA) techniques identified from 1 to 17 factors. The bi-factor model suggested that CRF was sufficiently unidimensional. CONCLUSIONS: CRF can be considered sufficiently unidimensional for applications that require unidimensionality. One such application, item response theory (IRT), will facilitate the development of short-form and computer-adaptive testing. This may further enable practical and accurate clinical assessment of CRF.}, keywords = {*Factor Analysis, Statistical, *Quality of Life, Aged, Chicago, Fatigue/*etiology, Female, Humans, Male, Middle Aged, Neoplasms/*complications, Questionnaires}, author = {Lai, J-S. and Crane, P. K. and Cella, D.} }